Picture this: thousands of years ago, humans thrived on diets rich in fiber, packed with tough plant materials like cellulose. Back then, our guts were full of specialized bacteria that could break down these fibers, turning them into fuel for our bodies. Fast forward to today, and with the rise of processed foods and low-fiber diets, many of these helpful microbes have vanished from our guts. But what if bringing them back could unlock new ways to boost our health? Our latest discovery has … [Read more...]
Microbial Diplomacy Unveiled: How Plasmid Coded Defense Systems Forge Peace in Our Guts
Our recent publication in Nature Microbiology presents findings elucidating the complex dynamics of gut microbial communities, with a focus on the role of plasmids in shaping these interactions. Below is a summary of our main findings: In the lively world of gut microbes, a fascinating tale of microbial warfare and peace unfolds—a story in which plasmids emerge as key players. Plasmids, often likened to "mini-chromosomes," are genetic backpacks bacteria carry alongside their primary … [Read more...]
Sabrina’s summer internship at the Mizrahi Lab
Shalom! My name is Sabrina Liu, and I am a rising junior from MIT interning at the Mizrahi lab this summer through the MISTI Israel program. Though I am majoring in Biological Engineering, most of the previous research I was involved in at the Koch Institute involved mechanical engineering in relation to biomedical devices. I was excited to not only work in the Mizrahi lab and learn wet lab/analysis techniques directly related to my major, but to meet diverse people and immerse myself in a new … [Read more...]
Let the Idos begin… Not an undergrad anymore
Hello! My name is Ido, and I’ve been a member of the Mizrahi lab for the past two years. During my undergraduate degree, my involvement in the group began as a lab technician, a year later I become a bachelors project student. Two years have passed and, these days, I am beginning my master degree here in Mizrahi's lab. At the end of my undergraduate studies, I went through a motivational crisis. Studying for exams semester after semester just for the sake of good grades felt … [Read more...]
Itzik talks in Hebrew about the rumen microbiome and microbial ecology in “MedabriMada” a leading popular science podcast
Itzik is talking about the rumen microbiome and microbial ecology in Hebrew with Shimon and Yomiran in ”Medabrimmada” - Talking about science - a wonderful podcast platform for popular science Click here to listen … [Read more...]
Engineering cell consortia to eating plant fibers: Tome IV By Sarah Morais
We have just published the 4th paper in our sequel story on Lactobacillus plantarum metabolic engineering! We have termed it "Rapid adaptation for fiber degradation by changes in plasmid stoichiometry within Lactobacillus plantarum at the synthetic community level "as we found that microbes can increase their fiber degradation capability as a community if they are synthetically evolved in the laboratory to do that. This story in fact began in 2011 when I first met Itzik and … [Read more...]
The rumen microbiome has a long term “memory” of early life events that could be used to manipulate and predict its assembly. By Ori furman
This story begins at a dairy science convention in Jerusalem. When I (Ori Furman) was about to graduate from my Master’s degree, in 2013. I was interested in pursuing the same course and to continue studying ruminants, a topic that had intrigued me since my high school days in an agricultural school. I specifically was interested in exploring the mechanism that drives the function of the rumen microbiome. I, therefore, decided to attend the Mizrahi group lectures, where I met me Profesor … [Read more...]
Life is like a box of chocolate, you never know what you get.- My time with the Mizrahi group during Corona pandemic
Hey there, my name is Johanna, 22 years old, and I am from Germany. I visited Israel and the MizrahiLab in March 2020 for 6 weeks. Or at least I tried to! Because my box of chocolate was not only filled with an awesome country, a new language, many very kind people, new experiences and interesting research, but it was also filled with the problems of the corona virus pandemic. As a German I am used to be on time and like it best when everything goes as planned. But during my stay in Israel … [Read more...]
Hello and Shalom y’all! Come check out our amazing internship experience at the Mizrahi Lab
Greetings from sunny Be’er Shevah. My name is Sam and I am a rising senior studying microbiology at the Albany College of Pharmacy and Health Sciences. I am on a program called Onward Israel, which provides highly subsidized internships to students from around the world who want to experience working life in Israel. And my name is Leyla I came from Turkey and my major is molecular biology and genetics. My school requires that students do a mandatory internship for 30 days. And I searched … [Read more...]
Our collaborative research on marine iguanas in the Galapagos
Global warming increases the strength and frequency El Niño events, affecting marine ecosystems along the equatorial pacific region. One of the best-documented examples of the effect of this extreme climatic event on marine biodiversity is found in the Galapagos Islands. There, the rise in water temperatures forces changes in the diet of marine iguanas that have led to massive populations collapses (80-90% of all individuals). The collapse in iguana populations is caused by the shifts in algal … [Read more...]