Congratulation to Inna for the recent publication in Cell Reports

Though it wasn’t easy, it showed that hard work and a collaborative lab effort eventually pay off. 

In her work Inna showed that:

  • 3D STROM can be used to resolve the structure of the ESCRT machine in cytokinesis.
  • ESCRT-III organizes into narrowing cortical spirals to drive abscission.
  • Abscission involves polymerization and depolymerization of the ESCRT-III spiral.
  • Depletion of individual ESCRT components affects ESCRT-III structure and function.

To read the entire story

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