About
Our lab maintains a highly interdisciplinary approach where biologists, chemists, and physicists work together in order to understand how molecular machines function with a goal to apply this insights into artificial proteins. We keep a collaborative atmosphere, where all lab members can develop their intellect and skills. The lab is a major contributor to the development of Cryo-EM as a major scientific module serving the Israeli community.
Our Mission
We are interested in how proteins sense and respond to cues in their environment. Our main tools are cryo-electron microscopy (Cryo-EM), which enables the structure determination of proteins, and spectroscopy, which can detect and characterize ligands. We are developing strategies to integrate the data from these modalities to achieve our goals.
We focus our efforts on several scientifically and medically important molecular machines:
1. AAA+ ATPases
2. Intracellular ferritin trafficking
