{"id":155,"date":"2018-09-03T06:07:47","date_gmt":"2018-09-03T06:07:47","guid":{"rendered":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/?page_id=155"},"modified":"2026-01-26T13:19:16","modified_gmt":"2026-01-26T13:19:16","slug":"list-of-publications","status":"publish","type":"page","link":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/?page_id=155","title":{"rendered":"List of publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"155\" class=\"elementor elementor-155\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6a7cf9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a6a7cf9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7669274\" data-id=\"7669274\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-66188cc elementor-widget elementor-widget-text-editor\" data-id=\"66188cc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h1><b>\u00a0<span style=\"font-size: 2rem;\">List of Publications<\/span><\/b><\/h1><div><span style=\"font-weight: bold;\">2026<\/span><\/div><div>\u00a0<\/div><div>Shtolz, N., Dadon, S. and Mishmar, D. Hypoxia leads to reduced mito-nuclear gene expression and increased mtDNA transcriptional pausing in human cells\u200f. Communications Biology (2026) <a href=\"https:\/\/www.nature.com\/articles\/s42003-025-09457-y\">https:\/\/www.nature.com\/articles\/s42003-025-09457-y<\/a> \u200f<\/div><div>\u00a0<\/div><div><span style=\"font-weight: bold;\">2025<\/span><br \/><b><br \/><\/b><span style=\"font-size: 1rem;\">Medini, H.,\u00a0<\/span><span style=\"font-size: 1rem;\">Mishmar, D.\u00a0<\/span>Vertebrates show coordinated elevated expression of mitochondrial and nuclear genes after birth. Genome Research 35 (3): 459-474 (2025). <a href=\"https:\/\/genome.cshlp.org\/content\/35\/3\/459\">link<\/a><\/div><div>\u00a0<\/div><div>This paper was selected to the cover of Genome Research March 2025 issue:\u00a0<\/div><div><a href=\"https:\/\/genome.cshlp.org\/content\/35\/3.cover-expansion\">https:\/\/genome.cshlp.org\/content\/35\/3.cover-expansion<\/a><\/div><div>\u00a0<\/div><p><span style=\"font-weight: bold;\">2023<\/span><\/p><p>Mishmar, D., Carmel, L., Shema, E. &amp; Falik-Zaccai, Z. Universities should denounce terrorism and antisemitism. Nature 623, 483 (2023). https:\/\/doi.org\/10.1038\/d41586-023-03540-2. <a href=\"https:\/\/www.nature.com\/articles\/d41586-023-03540-2\">link<\/a><\/p><p>Shtolz, N., Mishmar, D. The metazoan landscape of mitochondrial DNA gene order and content is shaped by selection and affects mitochondrial transcription. Commun Biol 6, 93 (2023). https:\/\/doi.org\/10.1038\/s42003-023-04471-4. <a href=\"https:\/\/www.nature.com\/articles\/s42003-023-04471-4\">link<\/a><span style=\"font-weight: bold; font-size: 1rem;\">\u00a0<\/span><\/p><p><span style=\"font-weight: bold;\">2022<\/span><\/p><p>Papier, O., Minor, G., Medini, H., Mishmar, D.\u00a0<span style=\"font-size: 1rem;\">Coordination of mitochondrial and nuclear gene-expression regulation in health, evolution, and disease,\u00a0<\/span><span style=\"font-size: 1rem;\">Current Opinion in Physiology,<\/span><span style=\"font-size: 1rem;\">Volume 27: <\/span><span style=\"font-size: 1rem;\">100554 (2022).<\/span><span style=\"font-size: 1rem;\">ISSN 2468-8673,<\/span><span style=\"font-size: 1rem;\">https:\/\/doi.org\/10.1016\/j.cophys.2022.100554. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2468867322000724?via%3Dihub\">link<\/a><\/span><\/p><p>Meshnik, L., Bar-Yaacov, D., Kasztan, D. et al. Mutant C. elegans mitofusin leads to selective removal of mtDNA heteroplasmic deletions across generations to maintain fitness. BMC Biol 20, 40 (2022). https:\/\/doi.org\/10.1186\/s12915-022-01241-2. <a href=\"https:\/\/bmcbiol.biomedcentral.com\/articles\/10.1186\/s12915-022-01241-2\">link<\/a><\/p><p>Cohen, T., Medini, H., Mordechai, C. et al. Human mitochondrial RNA modifications associate with tissue-specific changes in gene expression, and are affected by sunlight and UV exposure. Eur J Hum Genet, 30(12):1363-1372 (2022). https:\/\/doi.org\/10.1038\/s41431-022-01072-3. <a href=\"https:\/\/www.nature.com\/articles\/s41431-022-01072-3\">link<\/a><\/p><p><span style=\"font-weight: bold;\">2021<\/span><\/p><p>Medini, H. Zirman, A. and Mishmar, D. Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis. iScience\u00a0<span style=\"font-size: 1rem;\">(2021),<\/span><span style=\"font-size: 1rem;\">\u00a0https:\/\/doi.org\/10.1016\/j.isci.2021.103471. <a href=\"https:\/\/www.cell.com\/iscience\/fulltext\/S2589-0042(21)01442-5\">link<\/a><\/span><\/p><p>Bershtein, S., Kleiner, D. &amp; Mishmar, D. Predicting 3D protein structures in light of evolution. Nat Ecol Evol 5, 1195\u20131198 (2021). https:\/\/doi.org\/10.1038\/s41559-021-01519-8. <a href=\"https:\/\/www.nature.com\/articles\/s41559-021-01519-8?proof=t%29\">link<\/a><\/p><p>Medini, H., Cohen, T. &amp; Mishmar, D. Mitochondrial gene expression in single cells shape pancreatic beta cells&#8217; sub-populations and explain variation in insulin pathway. Sci Rep 11, 466 (2021). https:\/\/doi.org\/10.1038\/s41598-020-80334-w. <a href=\"https:\/\/www.nature.com\/articles\/s41598-020-80334-w\">link<\/a><\/p><p><span style=\"font-weight: bold;\">2020<\/span><\/p><p>Levy T, Ventura T, De Leo G, Grinshpan N, Abu Abayed FA, Manor R, Savaya A, Sklarz MY, Chalifa-Caspi V, Mishmar D, Sagi A.\u00a0Two Homogametic Genotypes &#8211; One Crayfish: On the Consequences of Intersexuality. iScience. 2020 Oct 6;23(11):101652. doi: 10.1016\/j.isci.2020.101652. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33103088\/\">link<\/a><\/p><p>Medini H, Cohen T, Mishmar D. Mitochondria Are Fundamental for the Emergence of Metazoans: On Metabolism, Genomic Regulation, and the Birth of Complex Organisms [published online ahead of print, 2020 Aug 28]. Annu Rev Genet. 2020;10.1146\/annurev-genet-021920-105545. doi:10.1146\/annurev-genet-021920-105545. <a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-genet-021920-105545\">link<\/a><span style=\"font-size: 1rem;\">\u00a0<\/span><\/p><p>Mishmar, D. mtDNA in the crossroads of evolution and disease. Nat Rev Mol Cell Biol (2020). https:\/\/doi.org\/10.1038\/s41580-020-0213-4.\u00a0<a style=\"background-color: #ffeecc;\" href=\"https:\/\/www.nature.com\/articles\/s41580-020-0213-4#citeas\">link<\/a><b><br \/><\/b><\/p><p><b>2019<\/b><\/p><p><span style=\"font-size: 1rem;\">Barshad, G., Zlotnikov-Poznianski, N., Gal, L. et al. Disease-causing mutations in subunits of OXPHOS complex I affect certain physical interactions. Sci Rep 9, 9987 (2019) doi:10.1038\/s41598-019-46446-8. <\/span><a style=\"background-color: #ffeecc; font-size: 1rem;\" href=\"https:\/\/www.nature.com\/articles\/s41598-019-46446-8\">link<\/a><\/p><p>Mishmar D., Levin R., Naeem Mansur M., Sondheimer N., (2019).\u00a0The Mitochondrial Genome\u2013on Selective Constraints and Signatures at the Organism, Cell, and Single Mitochondrion Levels.\u00a0Front. Genet., doi:\u00a010.3389\/fgene.2019.01285. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fgene.2019.01285\/full\">link<\/a><\/p><p>Shtolz N.,\u00a0<span style=\"font-size: 1rem;\">Mishmar, D., (2019).\u00a0<\/span>The Mitochondrial Genome\u2013on Selective Constraints and Signatures at the Organism, Cell, and Single Mitochondrion Levels.\u00a0Front. Ecol. Evol., doi:\u00a010.3389\/fevo.2019.00342. <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fevo.2019.00342\/full\">link<\/a><\/p><p>Marom, S., Blumberg, A.,\u00a0<span style=\"font-size: 1rem;\">Kundaje, A.,\u00a0<\/span><span style=\"font-size: 1rem;\">Mishmar, D., (2019).\u00a0<\/span>mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis.\u00a0iScience,\u00a0doi:\u00a0<span style=\"font-size: 1rem;\">10.1016\/j.isci.2018.12.032. <a href=\"https:\/\/www.cell.com\/iscience\/fulltext\/S2589-0042(18)30262-1\">link<\/a><\/span><\/p><p><b style=\"font-size: 1rem;\">2018<\/b><\/p><p>Chalkia, D., Chang, Y. C., Derbeneva, O., Lvova, M., Wang, P., Mishmar, D., &#8230; &amp; Wallace, D. C. (2018). Mitochondrial DNA associations with East Asian metabolic syndrome. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1859(9), 878-892.<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0005272818301890\">\u200f link<\/a><\/p><p>Barshad, G., Marom, S., Cohen, T., &amp; Mishmar, D. (2018). Mitochondrial DNA transcription and its regulation: an evolutionary perspective. Trends in Genetics, doi:10.1016\/j.tig.2018.05.009. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0168952518301033\">link<\/a><\/p><p>Barshad, G., Blumberg, A., Cohen, T., &amp; Mishmar, D. (2018). Human primitive brain displays negative mitochondrial-nuclear expression correlation of respiratory genes. Genome research, doi:10.1101\/gr.226324.117. <a href=\"https:\/\/genome.cshlp.org\/content\/early\/2018\/06\/16\/gr.226324.117.abstract\">link<\/a><\/p><p>Blumberg, A., Danko, C. G., Kundaje, A., &amp; Mishmar, D. (2018). A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization. Genome research, doi:10.1101\/gr.230409.117.\u200f <a href=\"https:\/\/genome.cshlp.org\/content\/early\/2018\/07\/12\/gr.230409.117.abstract\">link<\/a><\/p><p><b>2017<\/b><\/p><p>Marom, S., Friger, M., &amp; Mishmar, D. (2017). MtDNA meta-analysis reveals both phenotype specificity and allele heterogeneity: a model for differential association. Scientific Reports, 7., 43449; doi: 10.1038\/srep43449\u200f <a href=\"https:\/\/www.nature.com\/articles\/srep43449#additional-information\">link<\/a><\/p><p>Levin.L &amp; Mishmar.D.(2017).The genomic landscape of evolutionary convergence in mammals, birds and reptiles. Nature Ecology &amp; Evolution,10.1038\/s41559-016-0041<a href=\"https:\/\/www.nature.com\/articles\/s41559-016-0041\"> link<\/a><\/p><p>Blumberg, A., Kundaje, A., Danko, C. G., &amp; Mishmar, D. (2017). Initiation of mtDNA transcription is followed by pausing, and diverge across human cell types and during evolution. Genome Research, gr-209924.\u200f\u00a0<a href=\"https:\/\/www.google.com\/url?hl=iw&amp;q=http:\/\/genome.cshlp.org\/content\/early\/2017\/02\/13\/gr.209924.116.full.pdf%2Bhtml&amp;source=gmail&amp;ust=1487145338234000&amp;usg=AFQjCNGeHhJAL3ahkcF9e57QYkr27bzUbQ\"> link<\/a><\/p><p><b>2016<\/b><\/p><p>Cohen T, Levin L, Mishmar D (2016) Ancient Out-of-Africa Mitochondrial DNA Variants Associate with Distinct Mitochondrial Gene Expression Patterns. PLoS Genet 12(11): e1006407. doi:10.1371\/journal.pgen.1006407 <a href=\"https:\/\/journals.plos.org\/plosgenetics\/article?id=info:doi\/10.1371\/journal.pgen.1006407\">link<\/a><\/p><p>Bar-Yaacov, D., I. Frumkin, Y. Yashiro, T. Chujo, Y. Ishigami, Y. Chemla, A. Blumberg, O. Schlesinger, P. Bieri, B. Greber, N. Ban, R. Zarivach, L. Alfonta, Y. Pilpel, T. Suzuki and D. Mishmar (2016). &#8220;Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates.&#8221; PLoS Biol 14(9): e1002557. <a href=\"https:\/\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.1002557\">link<\/a><\/p><p><b>2015<\/b><\/p><p>Bar-Yaacov D, Hadjivasiliou Z, Levin L, Barshad G, Zarivach R, Bouskila A, Mishmar D. Mitochondrial involvement in vertebrate speciation? The case of mito-nuclear genetic divergence in chameleons. Genome Biol Evol . 2015 Dec 1;7(12):3322-36. <a href=\"https:\/\/academic.oup.com\/gbe\/article\/7\/12\/3322\/2467113\">link<\/a><\/p><p>Levin L, Bar-Yaacov D, Bouskila A, Chorev M, Carmel L, Mishmar D. LEMONS\u2013A Tool for the Identification of Splice Junctions in Transcriptomes of Organisms Lacking Reference Genomes. PloS one. 2015;10(11). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4659627\/\">link<\/a><\/p><p>Levin L and Mishmar D. A Genetic View of the Mitochondrial Role in Ageing: Killing Us Softly. In: Atzmon G (ed).\u00a0 Longevity Genes, 2015\u200f (Springer). <a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-1-4939-2404-2_4#page-1\">link<\/a><\/p><p>Valenci I, Yonai L, Bar-Yaacov D, Mishmar D and Ben-Zvi A. \u201cParkin modulates heteroplasmy of truncated mtDNA in Caenorhabditis elegans\u201d. Mitochondrion 2015; 20: 64-70. doi: 10.1016\/j.mito.2014.11.001. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567724914001639\">link<\/a><\/p><p><b>2014<\/b><\/p><p>Levin L, Blumberg A, Barshad G, Mishmar D. Mito-nuclear co-evolution: the positive and negative sides of functional ancient mutations.Frontiers in Genetics 2014;5:448. doi:10.3389\/fgene.2014.00448.\u00a0 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4274989\/pdf\/fgene-05-00448.pdf\">link<\/a><\/p><p>Gershoni M, Levin L, Ovadia O, Toiw Y, Shani N, Dadon S, Barzilai N, Bergman A, Atzmon G, Wainstein J, Tsur A, Nijtmans L, Glaser B, Mishmar D. Disrupting mitochondrial-nuclear co-evolution affects OXPHOS complex I integrity and impacts human health. Genome Biol Evol published online October 9, 2014, 6: 2665-2680. <a href=\"http:\/\/gbe.oxfordjournals.org\/content\/6\/10\/2665.short\">link<\/a><\/p><p>Blumberg A, Sailaja BS, Kundaje A, Levin L, Dadon S, Shmorak S, Shaulian E, Meshorer E, Mishmar D. Transcription Factors Bind Negatively Selected Sites within Human mtDNA Genes. Genome Biol Evol published online October 8, 2014, 6: 2634-2646. <a href=\"http:\/\/gbe.oxfordjournals.org\/content\/6\/10\/2634.short\">link<\/a><\/p><p><b>2013<\/b><\/p><p>Bar-Yaacov D, Bouskila A, Mishmar D. The first chameleon transcriptome: Comparative genomic analysis of the OXPHOS system reveals loss of COX8 in iguanian lizards. Genome Biol Evol. published online September 4, 2013 <a href=\"http:\/\/gbe.oxfordjournals.org\/content\/5\/10\/1792.short#xref-corresp-1-1\">link<\/a><\/p><p>Bar-Yaacov D, Avital G, Levin L, Richards A, Hachen N, Jaramillo BR, Nekrutenko A, Zarivach R, and Mishmar D. RNA-DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA. Genome Research. published online August 2, 2013 <a href=\"https:\/\/genome.cshlp.org\/content\/early\/2013\/08\/02\/gr.161265.113.abstract\">link<\/a><\/p><p>Levin L, Zhidkov I, Gurman Y, Hawlena H, and Mishmar D. Functional Recurrent Mutations in the Human Mitochondrial Phylogeny \u2013 Dual Roles in Evolution and Disease. Genome Biol Evol. published online April 5, 2013 <a href=\"http:\/\/gbe.oxfordjournals.org\/content\/early\/2013\/04\/05\/gbe.evt058.short\">link<\/a><\/p><p><b>2010-2012<\/b><\/p><p>Avital G, Buchshtav M, Zhidkov I, Tuval Feder J, Dadon S, Rubin E, Glass D, Spector TD and Mishmar D. Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins. Hum Mol Genet. 2012 Jul 10.<a href=\"http:\/\/hmg.oxfordjournals.org\/content\/early\/2012\/07\/10\/hmg.dds245.full\">link<\/a><\/p><p>Bar Yaacov D, Arbel-Thau K, Zilka Y, Ovadia O, Bouskila and Mishmar, D. (2012) Mitochondrial DNA Variation, but Not Nuclear DNA, Sharply Divides Morphologically Identical Chameleons along an Ancient Geographic Barrier. PloS one 7(3):e31372.doi:10.1371\/journal.pone.0031372. <a href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0031372\">link<\/a><\/p><p>Zhidkov, I., Nagar, T., Mishmar, D. &amp; Rubin, E. MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences. Mitochondrion (2011).<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567724911002728\">link<\/a><\/p><p>Bar-Yaacov, D., Blumberg, A. &amp; Mishmar, D. Mitochondrial-nuclear co-evolution and its effects on OXPHOS activity and regulation.Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms (2011). <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874939911001842\">link<\/a><\/p><p>Zhidkov, I., Cohen, R., Geifman, N., Mishmar, D. &amp; Rubin, E. CHILD: a new tool for detecting low-abundance insertions and deletions in standard sequence traces. Nucleic Acids Research 39, e47 (2011).<a href=\"http:\/\/nar.oxfordjournals.org\/content\/39\/7\/e47.short\">link<\/a><\/p><p>Mishmar D. and Zhidkov, I. (2010). Evolution and disease converge in the mitochondrion, BBA-Bioenergetics, 1797: 1099-104. . <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20074547\">link<\/a><\/p><p>Gershoni, M. Fuchs, A., Shani, N., Fridman, Y., Corral-Debrinski, M., Aharoni, A., Frishman, D. and Mishmar, D. (2010). Co-evolution predicts direct interactions between mtDNA and nuclear DNA-encoded subunits of oxidative phosphorylation complex I, Journal of Molecular biology, 404: 158\u2013171. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20868692\">link<\/a><\/p><p>Amar, S., Ovadia, O., Maier, W., Ebstein, R., Belmaker RH, Mishmar, D. and Agam, G. (2010). Copy number variation of the SELENBP1 gene in schizophrenia, Behavioral and Brain Functions, 6: 40. <a href=\"https:\/\/behavioralandbrainfunctions.biomedcentral.com\/articles\/10.1186\/1744-9081-6-40\">link<\/a><\/p><p>o\u00a0 \u00a0In this Behavioral and Brain Functions paper Prof. Agam and I are co-corresponding authors.<\/p><p>Garbian, Y., Ovadia, O., Dadon, S. and Mishmar, D. (2010). Gene expression patterns of oxidative phosphorylation complex I subunits are organized in modules PloS one, 5(4): e9983 . link<\/p><p><b>2007-2009<\/b><\/p><p>Feder, J. Ovadia, O., Blech, I., Cohen, J., Wainstein, J., Harman-Boehm, I., Glaser, B., and Mishmar, D. (2009). Parental diabetes status reveals association of Mitochondrial DNA Haplogroup J1 with Type 2 Diabetes , BMC Med Genet, 10(1):60. <a href=\"https:\/\/bmcmedgenet.biomedcentral.com\/articles\/10.1186\/1471-2350-10-60\">link<\/a><\/p><p>Suissa, S., Wang, Z., Poole, J., Wittkopp, S., Feder, J., Shutt, TE, Wallace, DC, Shadel, GS and Mishmar, D. (2009). Ancient mtDNA genetic variants modulate mtDNA transcription and replication, PLoS Genetics, 5 (5): e1000474.\u00a0 <a href=\"https:\/\/journals.plos.org\/plosgenetics\/article?id=10.1371\/journal.pgen.1000474\">link<\/a><\/p><p>Gershoni, M., Templeton, AR and Mishmar, D. (2009). Mitochondrial biogenesis as a major motive force of speciation, BioEssays, 31(6):642-650.\u00a0 <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bies.200800139\/full\">link<\/a><\/p><p>o\u00a0 \u00a0This BioEssays paper was thoroughly discussed in: Lane, N. (2009). Nature, 462: 272-74.<\/p><p>Zhidkov, I., Livneh, EA, Rubin, E. and Mishmar, D. (2009). mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints, Genome Research, 19:576-580. (Cover article).\u00a0<a href=\"http:\/\/genome.cshlp.org\/content\/19\/4\/576.short\"> link<\/a><\/p><p>o\u00a0 \u00a0This Genome Research paper was selected to present the cover page of the April issue of the Journal, 2009.<\/p><p>Potluri, P., Davila, A., Ruiz-Pesini, E., Mishmar, D., O\u2019Hearn, S., Hancock, S., Simon, M., Scheffler, I.E., Wallace, D.C., and Procaccio, V.F. (2009). Progressive Complex I-Specific Neurodegenerative Disease Caused by Faulty Nuclear-Cytoplasmic Interaction, Molecular Genetics and Metabolism, 96(4):189-95.\u00a0 <a href=\"https:\/\/www.sciencedirect.com\/science?_ob=ArticleURL&amp;_udi=B6WNG-4VGMPBK-1&amp;_user=32401&amp;_coverDate=04%2F30%2F2009&amp;_rdoc=1&amp;_fmt=high&amp;_orig=gateway&amp;_origin=gateway&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_searchStrId=1690542203&amp;_rerunOrigin=scholar.google&amp;_acct=C000004078&amp;_version=1&amp;_urlVersion=0&amp;_userid=32401&amp;md5=2d1615fecbde8d777da3a761ced733b1&amp;searchtype=a\">link\u00a0<\/a><\/p><p>\u00b7<\/p><p>Kozminsky-Atias, A., Bar-Shalom, A., Mishmar, D., and Zilberberg N. (2008) Assembling an arsenal, the scorpion way. BMC Evolutionary Biology 8(1):333. <a href=\"https:\/\/bmcevolbiol.biomedcentral.com\/articles\/10.1186\/1471-2148-8-333\">link<\/a><\/p><p>Brandon MC, Ruiz-Pesini E, Mishmar D, Procaccio V, Lott MT, Nguyen KC, Spolim S, Patil U, Baldi P, Wallace DC. (2009). MITOMASTER: a bioinformatics tool for the analysis of mitochondrial DNA sequences. Hum Mutat. 30(1):1-6.<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/humu.20801\"> link<\/a><\/p><p>Feder, J., Blech, I., Ovadia, O., Wainstein, J., Raz, I., Dadon, S., Arking DE, Glaser, B. and Mishmar D. (2008). Mitochondrial DNA Haplogroups Alter Susceptibility to Complications of Type 2 Diabetes Mellitus in three Jewish populations, BMC Genomics, 9: 198. <a href=\"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/1471-2164-9-198\">link<\/a><\/p><p>Amar, S., Shamir A., Ovadia, O., Blanaru, M., Reshef, A., Kremer, I., Rietschel, M., Schulze, TG, Maier, W., Belmaker, RH, Ebstein, RE, Agam, G. and Mishmar D. (2007). Mitochondrial DNA HV lineage increases the susceptibility to schizophrenia among Israeli Arabs,Schizophrenia Research, 94(1-3): 354-8. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17566709\">link<\/a><\/p><p>Mishmar, D. and Gershoni, M. (2007). Treating speciation processes as complex traits, Nature Reviews Genetics, 8: doi:10.1038\/nrg1968-c1. <a href=\"https:\/\/www.nature.com\/articles\/nrg1968-c1\">link<\/a><\/p><p>Feder, J., Ovadia, O., Glaser, B. and Mishmar, D. (2007). Ashkenazi Jewish mtDNA haplogroup distribution varies among distinct subpopulations: lessons of population sub-structure in a closed group, European Journal of Human genetics, 15(4):498-500.\u00a0 <a href=\"https:\/\/www.nature.com\/articles\/5201764?iframe=true&amp;width=100%25&amp;height=100%25\">link<\/a><\/p><p>Ruiz-Pesini, E., Lott, M, Procaccio, V, Poole, J., Brandon, M., Mishmar, D., Yi, C., Kreuziger, J., Baldi, P., Wallace, D. (2007). An Enhanced MITOMAP with a Global mtDNA Mutational Phylogeny, Nucleic Acid Research 35(Database issue):D823-8. <a href=\"http:\/\/nar.oxfordjournals.org\/content\/35\/suppl_1\/D823.short\">link<\/a><\/p><p><b>2004-2006<\/b><\/p><p>Mishmar, D., Ruiz-Pesini, E., Mondragon-Palomino, M., Procaccio, V., Gaut, B., and Wallace, D.C (2006). Adaptive Selection of Mitochondrial Complex I Subunits during Primate Radiation, Gene, 378: 11-18.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16828987\"> link<\/a><\/p><p>Ruiz-Pesini, E., Mishmar, D., Brandon, M., and Wallace, D.C. (2004). Effects of purifying and adaptive selection on regional variation in human mtDNA, Science, 303(5655): 223-6.\u00a0 <a href=\"http:\/\/science.sciencemag.org\/content\/303\/5655\/223\">link<\/a><\/p><p>Mishmar, D., Ruiz-Pesini, E., Brandon, M., and Wallace, D.C. (2004). Mitochondrial DNA-like sequences in the Nucleus (NUMTs): Insights into our African origins and the mechanism of foreign DNA integration. Human Mutation, 23(2): 125-33.\u00a0 <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/humu.10304\">link<\/a><\/p><p><b>Until 2003:<\/b><\/p><p>Wallace, D.C., Ruiz-Pesini, E., and Mishmar, D. (2003). MtDNA Variation, Climatic Adaptation, Degenerative Diseases and Longevity, Cold Spring Harb Symp Quant Biol, 68:479-86<a href=\"http:\/\/symposium.cshlp.org\/content\/68\/471.extract\"> link<\/a><\/p><p>Mishmar, D., Ruiz-Pesini, E., Golik, P., Macaulay, V., Clark A.G., Hosseini, S., Brandon, M., Easley, K., Chen, E., Brown, M.D., Sukernik, R.I., Olckers, A. and Wallace, D.C. (2003). Natural selection shaped Regional Mitochondrial DNA variation in humans, Proc.Natl.Acad.Sci., 100(1):171-176.\u00a0<a href=\"http:\/\/www.pnas.org\/content\/100\/1\/171.short\"> link<\/a><\/p><p>Mishmar, D., Mandel-Gutfreund, Y., Margalit, H., Rahat, A., and Kerem, B. (1999). Common fragile sites: G-band characteristics within an R-band, The American Journal of Human Genetics, 64: 908-910. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1377812\/\">link<\/a><\/p><p>Mishmar, D., Rahat, A., Scherer, S.W., Nyakatura, G., Hinzmann, B., Kohwi, Y., Mandel-Gutfroind, Y., Lee, J.R., Drescher, B., Sas, D.E., Margalit, H., Platzer, M., Kohwi-Shigematsu, T., Weiss,A., Tsui, L-C., Rosenthal, A. and Kerem, B. (1998). Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of an SV40 integration site. Proc.Natl.Acad.Sci., 95(14):8141-8146.\u00a0 <a href=\"http:\/\/www.pnas.org\/content\/95\/14\/8141.short\">link<\/a><\/p><p>Mishmar, D. (1997). Is He Our Ancestor? Galilleo, 24: 56-59 (Hebrew)<\/p><p>Reshef, D. (1994). Human origins: prehistory in the biology class, Journal for Biology Teachers, 137b: 65-68 (Hebrew)<\/p><p>Reshef, D. and Smith,P. (1993). Two Skeletal Remains from Hiam El Sagha, Revue Biblique, 101: 260-269\u00a0<a href=\"https:\/\/www.jstor.org\/stable\/44089154?seq=1\">https:\/\/www.jstor.org\/stable\/44089154?seq=1<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u00a0List of Publications 2026\u00a0Shtolz, N., Dadon, S. and Mishmar, D. Hypoxia leads to reduced mito-nuclear gene expression and increased mtDNA transcriptional pausing in human cells\u200f. Communications Biology (2026) https:\/\/www.nature.com\/articles\/s42003-025-09457-y \u200f\u00a02025Medini, H.,\u00a0Mishmar, D.\u00a0Vertebrates show coordinated elevated expression of mitochondrial and nuclear genes after birth. Genome Research 35 (3): 459-474 (2025). link\u00a0This paper was selected to the &hellip; <a href=\"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/?page_id=155\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;List of publications&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-155","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/pages\/155","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=155"}],"version-history":[{"count":40,"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/pages\/155\/revisions"}],"predecessor-version":[{"id":693,"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=\/wp\/v2\/pages\/155\/revisions\/693"}],"wp:attachment":[{"href":"https:\/\/lifewp.bgu.ac.il\/wp\/dmishmar\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=155"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}